2002: Epigenetic Mechanisms in Human Disease
Washington, DC: Welcome to the website on the "Epigenetic Mechanisms in Human Disease" to be held at the NIH in Bethesda, MD April 30th and 31th, 2002. Speakers include: T. Bestor (USA), V. Corces (USA), R. DePaulo (USA), A. Feinberg (USA), G. Hager (USA), Y.-M. Han (Korea), Y. Hayashizaki (Japan), S. Henikoff (USA), D. Higgs (UK), B. Horsthemke (Germany), B. Howard (USA), C.-L. Hsieh (USA), D. Lipman (USA), V. Lobanenkov (USA), M. Meguro (Japan), B. Migeon (USA), K. Muegge (USA), R. Nicholls (USA), R. Ohlsson (Sweden), M. Oshimura (Japan), E. Viegas-Pequignot (France), D. Preuss (USA), A. Razin (Israel), C. Sapienza (USA), M. Shirakawa (Japan), K. Sinclair (UK), B. Tycko (USA), T. Ushijima (Japan), W. Yasui (Japan), Y. Yu (USA), H. Zoghbi (USA).
ORGANIZERS: Terry Moody (Center for Cancer Research, NCI), Andrew Feinberg (Johns Hopkins School of Medicine), Mitsuo Oshimura (Tottori Univ., Japan), J. Carl Barrett (Center for Cancer Research, NCI)
Invited Speaker Presentations
The following is a list of the Environmental Epigenomics conference speakers and their addresses, along with links to their presentation abstracts and recordings. Audio is in MP3 format and video requires Shockwave Flash.
- Timothy Bestor — United States
- "Imprint Instability in Mammalian Reproduction"
Abstract / Audio / Video
- "Imprint Instability in Mammalian Reproduction"
- Victor Corces — United States
- "Chromatin Insulators and Nuclear Organization"
Abstract / Audio / Video
- "Chromatin Insulators and Nuclear Organization"
- Raymond De Paulo — United States
- "Genetics of Bipolar Disorder: Promises Versus Progress"
Abstract / Audio / Video
- "Genetics of Bipolar Disorder: Promises Versus Progress"
- Andrew Feinberg — United States
- "Epigenetic Instability in Human Cancer"
Abstract / Audio / Video
- "Epigenetic Instability in Human Cancer"
- Gordon Hager — United States
- "Epigenetics and Nuclear Receptor Function"
Abstract / Audio / Video
- "Epigenetics and Nuclear Receptor Function"
- Yong-Mahn Han — South Korea
- "DNA methylation and Cloning"
Abstract / Audio / Video
- "DNA methylation and Cloning"
- Yoshihide Hayashizaki — Japan
- "The Collection of Whole Transcriptome and its Application to Medical Research"
Abstract / Audio / Video
- "The Collection of Whole Transcriptome and its Application to Medical Research"
- Steven Henikoff — United States
- "Replication-independent Assembly of Chromatin Utilizes Variant H3 Histones"
Abstract / Audio / Video
- "Replication-independent Assembly of Chromatin Utilizes Variant H3 Histones"
- Douglas Higgs — United Kingdom
- "Structure and function of the ATRX protein"
Abstract / Audio / Video
- "Structure and function of the ATRX protein"
- Bernhard Horsthemke — Germany
- "The Prader-Willi/Angelman Syndromes"
Abstract / Audio / Video
- "The Prader-Willi/Angelman Syndromes"
- Bruce Howard — United States
- "Human Genome Screen for Regions Associated with Silencing or Remodeling"
Abstract / Audio / Video
- "Human Genome Screen for Regions Associated with Silencing or Remodeling"
- Ichizo Kobayashi — Japan
- "Restriction-Modification: Epigenetic Parasites Shaping the Gemone"
Abstract / Audio / Video
- "Restriction-Modification: Epigenetic Parasites Shaping the Gemone"
- David Lipman — United States
- "Computing Discoveries on the Genome"
Abstract / Audio / Video
- "Computing Discoveries on the Genome"
- Victor Lobanenkov — United States
- "The Unique Pairing of a Ubiquitous and a Male Germ Cell Specific Factor with the same 11 Zn-finger Domain Encoded by Two Paralagous Genes: CTCF at 16q22 and BORIS at 20q13are involved in Epigenetics of Normal biology and Cancer"
Abstract / Audio / Video
- "The Unique Pairing of a Ubiquitous and a Male Germ Cell Specific Factor with the same 11 Zn-finger Domain Encoded by Two Paralagous Genes: CTCF at 16q22 and BORIS at 20q13are involved in Epigenetics of Normal biology and Cancer"
- Makiko Meguro — Japan
- "An in vitro Assay System for Molecular Understanding of Genomic Imprinting involved in Human Diseases"
Abstract / Audio / Video
- "An in vitro Assay System for Molecular Understanding of Genomic Imprinting involved in Human Diseases"
- Barbara Migeon — United States
- "Species Differences in the Structure and Function of the Tsix/TSIX Antisense Gene suggests that its Role is Confined to Imprinted X-inactivation and explains Why X-inactivation is not Imprinted in Human Placenta"
Abstract / Audio / Video
- "Species Differences in the Structure and Function of the Tsix/TSIX Antisense Gene suggests that its Role is Confined to Imprinted X-inactivation and explains Why X-inactivation is not Imprinted in Human Placenta"
- Kathrin Muegge — United States
- "Lsh, a Modifier of Genomic Methylation"
Abstract / Audio / Video
- "Lsh, a Modifier of Genomic Methylation"
- Rolf Ohlsson — Sweden
- "Epigenetic States and Expression Domains in Development and Neoplasia: The CTCF and BORIS Connections"
Abstract / Audio / Video
- "Epigenetic States and Expression Domains in Development and Neoplasia: The CTCF and BORIS Connections"
- Mitsuo Oshimura — Japan
- "Disruption of Genomic Imprinting in Cancer"
Abstract / Audio / Video
- "Disruption of Genomic Imprinting in Cancer"
- Daphne Preuss — United States
- "Centromere Conformation and Control of Centromere-Linked Gene Expression in Arabidopsis"
Abstract / Audio / Video
- "Centromere Conformation and Control of Centromere-Linked Gene Expression in Arabidopsis"
- Carl Sapienza — United States
- "Selfish genes, the Phenotype Paradigm and Genome Evolution. 2: Epigenetic Structures"
Abstract / Audio / Video
- "Selfish genes, the Phenotype Paradigm and Genome Evolution. 2: Epigenetic Structures"
- Masahiro Shirakawa — Japan
- "Recognition of DNA Methylation Signals by Human Methylation-dependent Transcriptional Regulatory MBD1"
Abstract / Audio / Video
- "Recognition of DNA Methylation Signals by Human Methylation-dependent Transcriptional Regulatory MBD1"
- Kevin Sinclair — United Kingdom
- "Reprogramming the Donor Nucleus: Imprinting Disorders Following Nuclear Transfer"
Abstract / Audio / Video
- "Reprogramming the Donor Nucleus: Imprinting Disorders Following Nuclear Transfer"
- Benjamin Tycko — United States
- "Imprinting and growth control: Evidence from analysis of the Ipl/Tssc3 gene"
Abstract / Audio / Video
- "Imprinting and growth control: Evidence from analysis of the Ipl/Tssc3 gene"
- Toshikazu Ushijima — Japan
- "A Genome-Wide Picture of Aberrant Methylations in Human Cancers"
Abstract / Audio / Video
- "A Genome-Wide Picture of Aberrant Methylations in Human Cancers"
- Evani Viegas-Pequignot — France
- "ICF Syndrome, a Pathology Linked to a Heterochromatin Methylation Defect"
Abstract / Audio / Video
- "ICF Syndrome, a Pathology Linked to a Heterochromatin Methylation Defect"
- Wataru Yasui — Japan
- "Altered Histone Acetylation and Gene Expression in Cancer"
Abstract / Audio / Video
- "Altered Histone Acetylation and Gene Expression in Cancer"
- Yinhua Yu — United States
- "Modulation of ARHI and its Role in Carcinogenesis"
Abstract / Audio / Video
- "Modulation of ARHI and its Role in Carcinogenesis"
- Huda Zoghbi — United States
- "Characterization of MeCP2 Localization and a Mouse Model for RETT Syndrome"
Abstract / Audio / Video
- "Characterization of MeCP2 Localization and a Mouse Model for RETT Syndrome"