Dana Dolinoy, Ph.D., M.P.H.
Postdoctoral Fellow

Education

Duke University, Durham, North Carolina, B.A., 1998.

Harvard School of Public Health, Boston, Massachusetts, M.S., 2003.

Duke University, Graduate Research Assistant, University Program in Genetics and Integreated Toxicology Program, Duke University, Ph.D., Genetics, 2003 - 2007.

Duke University, Research Associate, 2007 - 2008.

University of Michigan School of Public Health, Assistant Professor of Environmental Health Sciences, 2008 - present.

Honors and Awards

1. Distinction Honors Thesis: Endocrine Disrupting Effects of Phthalate Plasticizers in the Environment

2. Pre-doctoral Fellowship, NIH Training Grant, 2003 - 2005.

3. AAAS/Science Program for Excellence in Science, 2005 - 2006.

4. Presidents Award from the Genetics and Environmental Mutagenesis Society (GEMS), 2007.

Research Experience

Environmental Scientist, Dames and Moore Inc., Atlanta, GA, 1998 - 1999.

Project Manager, Children's Environmental Health Initiative, Nicholas School of the Environment and Earth Sciences, Duke University, Durham, NC, 1999 - 2001.

Consultant and Technical Writer, Children's Environmental Health Initiative, Nicholas School of the Environment and Earth Sciences, Duke University, Durham, NC, 2001 - 2003.

Research Rotation, Marie Lynn Miranda, Spatial Analysis of Environmental Exposures, Duke University, Durham, NC, 2003 - 2003.

Doctoral Student, Randy L. Jirtle Laboratory, Environmental Influences Affecting Epigenetic DNA Methylation and Gene Regulation, 2003 - 2007.

Language and Research Skills

Language Skills: Conversational Spanish

Research Skills: Geographic Information Systems Spatial Analysis, Technical and Grant Writing, Human Subjects Research Certification, Animal Subjects Research Certification, Database Management

Presentations

1. Dolinoy DC. "Mapping for Prevention," Presentation to the New England Lead Committee, Fairlee, VT, June 10, 2002.

2. Miranda, M.L., Thomann, W., Abrams, M., Dolinoy DC, and Overstreet, M.A. "GIS Models of Childhood Exposures to Allergens and Asthma Triggers in the Home Environment." Data presented at the CDC National Asthma Conference, Atlanta, GA, October 23-25, 2002.

3. Dolinoy DC. and Miranda, M.L. "Methodologies for GIS-based Dispersion Modeling of Air Toxics Releases from TRI-Reporting and Non-TRI-Reporting Facilities: Impacts for ChildrenÕs Health and Environmental Justice." Presented at the Association of Schools of Public Health Conference on ChildrenÕs Environmental Health: Protecting Our Future. August 11-12, 2003.

4. Dolinoy DC. "Methods for GIS-Based Dispersion Modeling of Air Toxics Releases: Impacts for ChildrenÕs Health and Environmental Justice" Poster Presentation at the 21st International Neurotoxicology Conference Infant and Child Neurotoxicology Studies: Subtle and Long-Term Effects. February 10-13, 2004, Winner, 2nd Place Pre-Doctoral Student Competition

5. Dolinoy DC, Waterland, R.A., Weidman, J.R., and Jirtle, R.L. ÒMaternal Exposure to the Phytoestrogen Genistein Influences Epigenetic Gene Regulation in Mouse Offspring.Ó Poster presentation at the 22nd Annual Fall Meeting of the Genetics and Environmental Mutagenesis Society: DNA Methylation and its Toxicological Consequences. Chapel Hill, North Carolina. November 10, 2004. Winner, 1st Place Doctoral Student Competition.

6. Dolinoy DC, Waterland, R.A., and Jirtle, R.L. ÒMaternal Exposure to the Phytoestrogen Genistein Influences Epigenetic Gene Regulation in Avy Mouse Offspring and Protects Against Obesity.Ó Poster presentation at the North Carolina Society of Toxicology Meeting. Research Triangle Park, North Carolina. February 17, 2005. Winner, Student Award Competition.

7. Dolinoy DC, Waterland, R.A., and Jirtle, R.L. ÒMaternal Exposure to the Phytoestrogen Genistein Influences Epigenetic Gene Regulation in Avy Mouse Offspring and Protects Against Obesity.Ó Poster presentation at the 44th Annual Meeting of the Society of Toxicology. New Orleans, Louisiana. March 7-10, 2005.

8. Dolinoy DC, Waterland, R.A., Weidman, J.R., and Jirtle, R.L. ÒMaternal Exposure to the Phytoestrogen Genistein Influences Epigenetic Gene Regulation in Avy Mouse Offspring and Protects Against Obesity.Ó Poster presentation at the 6th Annual Sex and Gene Expression (SAGE) Conference. Winston Salem, North Carolina. March 17-19, 2005. Winner, Florence P. Haseltine Award for the Outstanding Poster Presentation by a New Investigator in Sex-Based Biology.

9. Dolinoy DC, Waterland, R.A., Weidman, J.R., and Jirtle, R.L. ÒMaternal Genistein Alters Coat Color and Protects Mouse Offspring from Obesity by Altering the Fetal Epigenome.Ó Poster presentation at the Environmental Epigenomics, Imprinting and Disease Susceptibility Conference. Durham, North Carolina. November 2-4, 2005.

10. Weidman, J.R., Dolinoy DC, and Jirtle, R.L. ÒRadiation and the Fetal Epigenome.Ó Poster presentation at the Department of Engergy Low-Dose Radiation Research Program VI, Washington, D.C. July 31 - August 3, 2006.

11. Dolinoy DC, Weidman, J.R., Maloney, K., and Jirtle, R.L. ÒMaternal Dietary Bisphenol A Decreases Mouse Offspring Methylation and Alters Offspring Histone Modifications.Ó Platform presentation at the Annual Meeting of the Environmental Mutagenesis Society. Vancouver, Canada. September 15 - 20, 2006. Winner, Student Award.

12. Dolinoy, D.C. Endocrine Active Compounds and the Fetal Epigenome. Epigenetics: From Mechanisms to Medicines Conference, Molecular Medicine Center, Dublin, Ireland, 2007.

13. Dolinoy, D.C. The Agouti Mouse Model: An Epigenetic Biosensor for Exploring the Impacts of Environmentally-Induced Nutritional and Chemical Alterations on Human Health. 33rd Annual ToxForum Summer Meeting, Aspen, Colorado, 2007.

14. Dolinoy, D.C. Maternal Nutrient Supplementation Counteracts Bisphenol-A-Induced DNA Hypomethylation in Early Development. Diet, Epigenetic Events, and Cancer Prevention Symposium, National Cancer Institute, Gaithersburg, Maryland, 2007.

15. Dolinoy, D.C. Epigenetic Gene Regulation: Linking Early Developmental Environment to Adult Disease. Annual Meeting, Gulf Coast Chapter Society of Toxicology, College Station, Texas, 2007.

16. Dolinoy, D.C. Epigenetics: The New Genetics of Toxicology. Center for Research on Occupational and Environmental Toxicology (CROET) Seminar Series, Oregon Health and Science University, Portland, Oregon, 2007.

Peer Reviewed Publications

1. Miranda, M.L., Yarger, L., and Dolinoy DC. Childhood Lead Exposure: Effects and Policy Options. Case Study used in the Duke University Environmental Science and Policy Program. April, 2000.

2. Miranda, M.L., Dolinoy DC, and Overstreet, M.A. Mapping for Prevention: GIS Models for Directing Childhood Lead Poisoning Prevention Programs. Environ. Health Perspect. 110: 947-953, 2002.

3. Miranda, M.L., Dolinoy DC, and Overstreet, M.A. GIS and childhood lead exposure: from research design to model development to community translation. Public Health GIS News and Information. No. 54, September, 2003.

4. Dolinoy DC, and Miranda, M.L. GIS modeling of air toxics releases from TRI-reporting and non-TRI-reporting facilities: impacts for environmental justice. Environ. Health Perspect. 112: 1717-1724, 2004.

5. Miranda M.L., and Dolinoy DC. Using GIS-based approaches to support research on neurotoxicants and other children's environmental health threats. Neurotoxicology 26: 223-228, 2005.

6. Dolinoy DC, Weidman, J.R., Waterland, R.A., and Jirtle, R.L. Maternal genistein alters coat color and protects Avy mouse offspring from obesity by modifying the fetal epigenome. Environ. Health Perspect. 14: 567-572, 2006. [PDF]

7. Weidman, J.R., Dolinoy DC, Maloney, K.A., Cheng, J.-F., and Jirtle, R.L. Imprinting of opossum Igf2r in the absence of differential methylation and Air. Epigenetics 1: 49-54, 2006. [PDF]

8. Waterland, R.A., Dolinoy DC, Lin, J.R., Smith, C.A., Shi, X., and Tahiliani, K.G. Maternal methyl supplements increase offspring DNA methylation at Axin fused. Genesis 44: 401-406, 2006. [PDF]

9. Bobetsis, Y.A., Barros, S.P., Lin, D.M., Weidman, J.R., Dolinoy DC, Jirtle, R.L. Boggess, K.A., Beck, J.D., and Offenbacher, S. Bacterial Infection Promotes DNA Hypermethylation. J. Dental Res. 86: 169-174, 2007. [PDF]

10. Dolinoy DC, Weidman, J.R., and Jirtle, R.L. Epigenetic gene regulation: Linking early developmental environment to adult disease. Reprod. Toxicol. 23: 297-307, 2007. [PDF]

11. Dolinoy DC, Das, R., Weidman, J.R., and Jirtle, R.L. Metastable epialleles, imprinting, and the fetal origins of adult diseases. Pediatric Res. 61: 30R-37R, 2007. [PDF]

12. Weidman, J.R., Dolinoy DC, Murphy, S.K., and Jirtle, R.L. Cancer susceptibility: epigenetic manifestation of environmental exposures. Cancer J. 13: 9-16, 2007. [PDF]

13. Dolinoy DC, Huang, D., and Jirtle, R.L. Maternal nutrient supplementation counteracts bisphenol A-induced DNA hypomethylation in early development. Proc. Natl. Acad. Sci. USA 104: 13056-13061, 2007. [Press Release] [PDF]

14. Dolinoy, D.C. The agouti mouse model: an epigenetic biosensor for nutritional and environmental alterations on the fetal epigenome. Nutr. Rev. 66 Suppl 1: S7-S11, 2008.

15. Dolinoy, DC, and Jirtle, R.L. Environmental epigenomics in human health and disease. Environ. Mol. Mutagen 9: 4-8. 2008. [PDF]

Other Publications

1. Miranda, M.L., Yarger, L. and Dolinoy DC. Childhood Lead Exposure: Effects and Policy Options. Case Study used in the Duke University Environmental Science and Policy Program, April 2000.

2. Miranda, M.L., Dolinoy DC, and Overstreet, M.A. GIS and childhood lead exposure: from research design to model development to community translation, Public Health GIS News and Information. No. 54, September 2003.

3. Dolinoy DC, and Jirtle. R.L. Guest Perspective: The Incorporation of Epigenetic Biological Effects Into Risk Assessment, Risk Policy Report, (In Preparation, 2006).

Hobbies

Home improvement, Deep-sea fishing, Hiking, Camping, Mountain biking

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